Bacterial antigens

Borrelia

Lyme borreliosis is tick-born infectious disease. Pathogens of Lyme borreliosis are bacteria from the group of Borrelia. Pathogenic genotypes are Borrelia garinii, B. afzelii, or B. burgdorferi sensu stricto. For detection of Lyme borreliosis, particularly immunogenic surface antigens such as OspC / OspA or DbpA, as well as VlsE and other proteins (p39, p41, p58, p83 / 100) are used. Most of the diagnostically relevant Borrelia antigens are available as both GST fusion and His-tag.

31

DbpA - Decorin-binding protein A

  Expression system Article No. Fusion Quantity
B. afzelii DbpA E.coli AGX-5-000-0139-0 GST 0.1 mg
    AGX-5-000-0139-1 GST 1.0 mg
Data sheet (87.6 KiB)
Safety data sheet (96.8 KiB)
  E.coli AGX-5-000-0376-0 6xHis 0.1 mg
    AGX-5-000-0376-1 6xHis 1.0 mg
         
Data sheet (87.4 KiB)
Safety data sheet (96.6 KiB)
B. burgdorferi DbpA E.coli AGX-5-000-0140-0 GST 0.1 mg
    AGX-5-000-0140-1 GST 1.0 mg
Data sheet (87.7 KiB)
Safety data sheet (96.8 KiB)
  E.coli AGX-5-000-0477-0 6xHis 0.1 mg
    AGX-5-000-0477-1 6xHis 1.0 mg
         
Data sheet (87.4 KiB)
Safety data sheet (96.7 KiB)
B. garinii DbpA E.coli AGX-5-000-0141-0 GST 0.1 mg
    AGX-5-000-0141-1 GST 1.0 mg
Data sheet (87.5 KiB)
Safety data sheet (96.6 KiB)
  E.coli AGX-5-000-0499-0 6xHis 0.1 mg
    AGX-5-000-0499-1 6xHis 1.0 mg
         
Data sheet (87.4 KiB)
Safety data sheet (96.6 KiB)
B. spielmanii DbpA E.coli AGX-5-000-0198-0 GST 0.1 mg
    AGX-5-000-0198-1 GST 1.0 mg
Data sheet (87.6 KiB)
Safety data sheet (96.7 KiB)

OspA - Outer surface protein A

  Expression system Article No. Fusion Quantity
B. afzelii OspA E.coli AGX-5-000-0143-0 GST 0.1 mg
    AGX-5-000-0143-1 GST 1.0 mg
Data sheet (87.7 KiB)
Safety data sheet (96.6 KiB)
  E.coli AGX-5-000-0197-0 6xHis 0.1 mg
    AGX-5-000-0197-1 6xHis 1.0 mg
Data sheet (87.6 KiB)
Safety data sheet (96.7 KiB)

OspC - Outer surface protein C

  Expression system Article No. Fusion Quantity
B. afzelii OspC E.coli AGX-5-000-0200-0 GST 0.1 mg
    AGX-5-000-0200-1 GST 1.0 mg
Data sheet (87.7 KiB)
Safety data sheet (96.6 KiB)
B. burgdorferi OspC E.coli AGX-5-000-0131-0 GST 0.1 mg
    AGX-5-000-0131-1 GST 1.0 mg
Data sheet (87.8 KiB)
Safety data sheet (96.8 KiB)
  E.coli AGX-5-000-0195-0 6xHis 0.1 mg
    AGX-5-000-0195-1 6xHis 1.0 mg
Data sheet (87.6 KiB)
Safety data sheet (96.7 KiB)
B. garinii OspC E.coli AGX-5-000-0132-0 GST 0.1 mg
    AGX-5-000-0132-1 GST 1.0 mg
Data sheet (87.7 KiB)
Safety data sheet (96.6 KiB)
  E.coli AGX-5-000-0196-0 6xHis 0.1 mg
    AGX-5-000-0196-1 6xHis 1.0 mg
Data sheet (87.5 KiB)
Safety data sheet (96.6 KiB)
B. garinii (Pbi) OspC E.coli AGX-5-000-0231-0 GST 0.1 mg
    AGX-5-000-0231-1 GST 1.0 mg
Data sheet (87.8 KiB)
Safety data sheet (97.0 KiB)
B. spielmanii OspC E.coli AGX-5-000-0199-0 GST 0.1 mg
    AGX-5-000-0199-1 GST 1.0 mg
Data sheet (87.8 KiB)
Safety data sheet (96.7 KiB)

OspC - Outer surface protein C dimeric

  Expression system Article No. Fusion Quantity
B. afzelii OspC dimeric E.coli AGX-5-000-0710-0 6xHis 0.1 mg
    AGX-5-000-0710-1 6xHis 1.0 mg
Data sheet (123.7 KiB)
Safety data sheet (96.9 KiB)
B. afzelii OspC dimeric E.coli AGX-5-001-0710-0 6xHis 0.1 mg
    AGX-5-001-0710-1 6xHis 1.0 mg
Data sheet (124.4 KiB)
B. burgdorferi OspC dimeric E.coli AGX-5-000-0711-0 6xHis 0.1 mg
    AGX-5-000-0711-1 6xHis 1.0 mg
Data sheet (87.7 KiB)
Safety data sheet (96.9 KiB)
B. garinii OspC dimeric E.coli AGX-5-000-0712-0 6xHis 0.1 mg
    AGX-5-000-0712-1 6xHis 1.0 mg
Data sheet (87.6 KiB)
Safety data sheet (96.9 KiB)

p83/100 - Borrelia family protein

  Expression system Article No. Fusion Quantity
B. afzelii p83/100 E.coli AGX-5-000-0443-0 GST 0.1 mg
    AGX-5-000-0443-1 GST 1.0 mg
Data sheet (87.6 KiB)
Safety data sheet (96.8 KiB)
  E.coli AGX-5-000-0492-0 6xHis 0.1 mg
    AGX-5-000-0492-1 6xHis 1.0 mg
Data sheet (87.4 KiB)
Safety data sheet (96.8 KiB)

p39 - Basic membrane protein A

  Expression system Article No. Fusion Quantity
B. afzelii p39 E.coli AGX-5-000-0135-0 GST 0.1 mg
    AGX-5-000-0135-1 GST 1.0 mg
Data sheet (87.2 KiB)
Safety data sheet (96.7 KiB)
  E.coli AGX-5-000-0379-0 6xHis 0.1 mg
    AGX-5-000-0379-1 6xHis 1.0 mg
Data sheet (87.4 KiB)
Safety data sheet (96.6 KiB)

p41 - Flagellar filament kDa core protein

  Expression system Article No. Fusion Quantity
B. burgdorferi p41 E.coli AGX-5-000-0136-0 GST 0.1 mg
    AGX-5-000-0136-1 GST 1.0 mg
Data sheet (87.2 KiB)
Safety data sheet (96.7 KiB)

p41 - Flagellar filament kDa core protein - N-term

  Expression system Article No. Fusion Quantity
B. burgdorferi p41 E.coli, N-term AGX-5-000-0190-0 GST 0.1 mg
    AGX-5-000-0190-1 GST 1.0 mg
Data sheet (87.3 KiB)
Safety data sheet (96.9 KiB)
  E.coli, N-term AGX-5-000-0476-0 6xHis 0.1 mg
    AGX-5-000-0476-1 6xHis 1.0 mg
Data sheet (87.5 KiB)
Safety data sheet (97.1 KiB)

p58 - Bacterial extracellular solute-binding protein, family 5

  Expression system Article No. Fusion Quantity
B. garinii p58 E.coli AGX-5-000-0204-0 GST 0.1 mg
    AGX-5-000-0204-1 GST 1.0 mg
Data sheet (181.2 KiB)
Safety data sheet (96.6 KiB)
  E.coli AGX-5-000-0389-0 6xHis 0.1 mg
    AGX-5-000-0389-1 6xHis 1.0 mg
Data sheet (87.4 KiB)
Safety data sheet (96.6 KiB)

Borrelia variable major protein (VMP) like sequence Expressed (VlsE)

  Expression system Article No. Fusion Quantity
B. afzelii VlsE E.coli AGX-5-000-0206-0 GST 0.1 mg
    AGX-5-000-0206-1 GST 1.0 mg
Data sheet (87.8 KiB)
Safety data sheet (96.6 KiB)
  E.coli AGX-5-000-0391-0 6xHis 0.1 mg
    AGX-5-000-0391-1 6xHis 1.0 mg
Data sheet (87.6 KiB)
Safety data sheet (96.7 KiB)
Helicobacter

Helicobacter pylori is a helical gramnegative rod that colonises the gastric mucosa of humans. The pathogen is widely distributed worldwide and is believed to be transmitted orally or by faeces. Important pathogenic factors of Helicobacter pylori are the tumorigenic protein CagA and the vacuolating cytotoxin VacA. The enzyme urease enables Helicobacter pylori to survive in the acidic gastric environment by cleavage of urea in ammonia and carbon dioxide. In addition to these antigens, there are other antigens such as the cysteine-rich protein HcpC, the gamma-glutamyltranspeptidase gGT and the chaperone GroEL. These proteins together enable antibody detection in serum with differentiation of pathogenicity factors.

16

Helicobacter pylori Catalase A

  Expression system Article No. Fusion Quantity
CatA E.coli AGX-5-000-0648-0 6xHis 0.1 mg
    AGX-5-000-0648-1 6xHis 1.0 mg
Data sheet (87.1 KiB)
Safety data sheet (96.9 KiB)

Helicobacter pylori Cytotoxicity-associated immunodominant antigen A

  Expression system Article No. Fusion Quantity
CagA E.coli AGX-5-000-0260-0 GST 0.1 mg
    AGX-5-000-0260-1 GST 1.0 mg
Data sheet (124.7 KiB)
Safety data sheet (384.1 KiB)
CagA E.coli AGX-5-000-0266-0 GST 0.1 mg
    AGX-5-000-0266-1 GST 1.0 mg
Data sheet (124.7 KiB)
Safety data sheet (384.2 KiB)
CagA E.coli AGX-5-000-0267-0 GST 0.1 mg
    AGX-5-000-0267-1 GST 1.0 mg
Data sheet (87.6 KiB)
Safety data sheet (96.8 KiB)
CagA E.coli AGX-5-000-0504-0 6xHis 0.1 mg
    AGX-5-000-0504-1 6xHis 1.0 mg
Data sheet (87.5 KiB)
Safety data sheet (97.0 KiB)

Helicobacter pylori Flagellin A

  Expression system Article No. Fusion Quantity
FlaA E.coli AGX-5-000-0699-0 6xHis 0.1 mg
    AGX-5-000-0699-1 6xHis 1.0 mg
Data sheet (87.8 KiB)
Safety data sheet (96.8 KiB)

Helicobacter pylori Gamma-glutamyltranspeptidase

  Expression system Article No. Fusion Quantity
gGT E.coli AGX-5-000-0533-0 6xHis 0.1 mg
    AGX-5-000-0533-1 6xHis 1.0 mg
Data sheet (87.4 KiB)
Safety data sheet (96.6 KiB)

Helicobacter pylori 60 kDa chaperonin

  Expression system Article No. Fusion Quantity
GroEL E.coli AGX-5-000-0299-0 GST 0.1 mg
    AGX-5-000-0299-1 GST 1.0 mg
Data sheet (87.6 KiB)
Safety data sheet (96.7 KiB)
GroEL E.coli AGX-5-000-0300-0 6xHis 0.1 mg
    AGX-5-000-0300-1 6xHis 1.0 mg
Data sheet (87.4 KiB)
Safety data sheet (96.7 KiB)

Helicobacter pylori Cystein-rich protein C

  Expression system Article No. Fusion Quantity
HcpC E.coli AGX-5-000-0303-0 GST 0.1 mg
    AGX-5-000-0303-1 GST 1.0 mg
Data sheet (87.2 KiB)
Safety data sheet (96.7 KiB)
HcpC E.coli AGX-5-000-0647-0 6xHis 0.1 mg
    AGX-5-000-0647-1 6xHis 1.0 mg
Data sheet (87.4 KiB)
Safety data sheet (96.7 KiB)

Helicobacter pylori Superoxide dismutase

  Expression system Article No. Fusion Quantity
SoD E.coli AGX-5-000-0672-0 6xHis 0.1 mg
    AGX-5-000-0672-1 6xHis 1.0 mg
Data sheet (87.4 KiB)
Safety data sheet (96.7 KiB)

Helicobacter pylori Urease subunit alpha

  Expression system Article No. Fusion Quantity
UreA E.coli AGX-5-000-0263-0 GST 0.1 mg
    AGX-5-000-0263-1 GST 1.0 mg
Data sheet (87.7 KiB)
Safety data sheet (96.7 KiB)
UreA E.coli AGX-5-000-0273-0 6xHis 0.1 mg
    AGX-5-000-0273-1 6xHis 1.0 mg
Data sheet (87.6 KiB)
Safety data sheet (96.7 KiB)

Helicobacter pylori Urease subunit beta

  Expression system Article No. Fusion Quantity
UreB E.coli AGX-5-000-0643-0 6xHis 0.1 mg
    AGX-5-000-0643-1 6xHis 1.0 mg
Data sheet (87.5 KiB)
Safety data sheet (96.7 KiB)

Helicobacter pylori vakuolisierendes Cytotoxin

  Expression system Article No. Fusion Quantity
VacA E.coli AGX-5-000-0487-0 6xHis 0.1 mg
    AGX-5-000-0487-1 6xHis 1.0 mg
Data sheet (87.9 KiB)
Safety data sheet (97.0 KiB)
Yersinia

Yersinia enterocolitica is the causative agent of febrile inflammation (enterocolitis or enteritis) resulting from food infection. The bacterium secretes numerous proteins from its cell into the environment. These proteins are called YOP (Yersinia outer protein). YOP´s act as virulence factors since they have anti-phagocytic properties and prevent phagocytosis in the context of immune defense. The genes encoding these proteins are located on a plasmid. Apathogenic Yersinia strains are missing this plasmid.

9

YopD - Yersinia enterocolitica outer protein D - N-term

  Expression system Article No. Fusion Quantity
YopD (N-term) E.coli AGX-5-000-0321-0 GST 0.1 mg
    AGX-5-000-0321-1 GST 1.0 mg
Data sheet (87.6 KiB)
Safety data sheet (97.0 KiB)
YopD E.coli AGX-5-000-0355-0 6xHis 0.1 mg
    AGX-5-000-0355-1 6xHis 1.0 mg
Data sheet (87.8 KiB)
Safety data sheet (96.7 KiB)

Yersinia enterocolitica outer protein E

  Expression system Article No. Fusion Quantity
YopE E.coli AGX-5-000-0108-0 GST 0.1 mg
    AGX-5-000-0108-1 GST 1.0 mg
Data sheet (87.6 KiB)
Safety data sheet (98.9 KiB)

Yersinia enterocolitica outer protein H

  Expression system Article No. Fusion Quantity
YopH E.coli AGX-5-000-0109-0 GST 0.1 mg
    AGX-5-000-0109-1 GST 1.0 mg
Data sheet (87.5 KiB)
Safety data sheet (98.9 KiB)
YopH E.coli AGX-5-000-0362-0 6xHis 0.1 mg
    AGX-5-000-0362-1 6xHis 1.0 mg
Data sheet (87.4 KiB)
Safety data sheet (96.7 KiB)

Yersinia enterocolitica Yersinia outer protein M

  Expression system Article No. Fusion Quantity
YopM E.coli AGX-5-000-0110-0 GST 0.1 mg
    AGX-5-000-0110-1 GST 1.0 mg
Data sheet (87.2 KiB)
Safety data sheet (98.9 KiB)
YopM E.coli AGX-5-000-0330-0 6xHis 0.1 mg
    AGX-5-000-0330-1 6xHis 1.0 mg
Data sheet (87.1 KiB)
Safety data sheet (96.7 KiB)

Yersinia enterocolitica Yersinia outer protein N

  Expression system Article No. Fusion Quantity
YopN E.coli AGX-5-000-0111-0 GST 0.1 mg
    AGX-5-000-0111-1 GST 1.0 mg
Data sheet (87.5 KiB)
Safety data sheet (98.9 KiB)
YopN E.coli AGX-5-000-0370-0 6xHis 0.1 mg
    AGX-5-000-0370-1 6xHis 1.0 mg
Data sheet (87.8 KiB)
Safety data sheet (96.7 KiB)
Treponema

Treponema pallidum subsp. pallidum is the causative agent of syphilis. Since Treponema is not cultivable, serological methods have a high priority in diagnosis. Antigens reactive with serum samples include TmpA and the 47-kDa, 17-kDa, and 15-kDa lipoproteins. These antigens are potentially useful as vaccine candidates or diagnostic markers.

6

Treponema pallidum p15

  Expression system Article No. Fusion Quantity
p15 E.coli AGX-5-000-0756-0 GST 0.1 mg
    AGX-5-000-0756-1 GST 1.0 mg
Data sheet (87.5 KiB)
Safety data sheet (96.7 KiB)
p15 E.coli AGX-5-000-0713-0 6xHis 0.1 mg
    AGX-5-000-0713-1 6xHis 1.0 mg
Data sheet (87.4 KiB)
Safety data sheet (96.6 KiB)

Treponema pallidum p17

  Expression system Article No. Fusion Quantity
p17 E.coli AGX-5-000-0757-0 GST 0.1 mg
    AGX-5-000-0757-1 GST 1.0 mg
Data sheet (87.1 KiB)
Safety data sheet (96.7 KiB)
p17 E.coli AGX-5-000-0715-0 6xHis 0.1 mg
    AGX-5-000-0715-1 6xHis 1.0 mg
Data sheet (87.4 KiB)
Safety data sheet (97.0 KiB)

Treponema pallidum p47

  Expression system Article No. Fusion Quantity
p47 E.coli AGX-5-000-0714-0 6xHis 0.1 mg
    AGX-5-000-0714-1 6xHis 1.0 mg
Data sheet (87.4 KiB)
Safety data sheet (96.6 KiB)

Treponemal membrane protein A

  Expression system Article No. Fusion Quantity
TmpA E.coli AGX-5-000-0687-0 GST 0.1 mg
    AGX-5-000-0687-1 GST 1.0 mg
Data sheet (87.6 KiB)
Safety data sheet (96.6 KiB)
Clostridium

Clostridium difficile is the causative agent of antibiotic associated colitis (AAC) and pseudomembranous colitis (PMC) mediated by the exotoxins A and B. Routine diagnosis of C. difficile is usually done by direct detection of both toxins A and B with enzyme immunoassays. Clostridium perfringens causes food-borne diseases and food infections. The Clostridium perfringens toxin epsilon (CPE), which is produced by type B and type D strains, is particularly relevant for diagnostic assays. Recombinantly expressed nontoxic fragments of clostridial toxins with similar or identical antigenic response are a good alternative to the expensive and difficult to purify native clostridial toxins.

5

Clostridium difficile NAD-specific glutamate dehydrogenase

  Expression system Article No. Fusion Quantity
GDH E.coli AGX-5-000-0213-0 GST 0.1 mg
    AGX-5-000-0213-1 GST 1.0 mg
Data sheet (87.2 KiB)
Safety data sheet (96.8 KiB)
GDH E.coli AGX-5-000-0256-0 6xHis 0.1 mg
    AGX-5-000-0256-1 6xHis 1.0 mg
Data sheet (87.5 KiB)
Safety data sheet (96.6 KiB)

Clostridium difficile Toxin A (C-terminus)

  Expression system Article No. Fusion Quantity
ToxA, C-term E.coli AGX-5-000-0114-0 GST 0.1 mg
    AGX-5-000-0114-1 GST 1.0 mg
Data sheet (87.6 KiB)
Safety data sheet (99.2 KiB)

Clostridium difficile Toxin B (C-terminus)

  Expression system Article No. Fusion Quantity
ToxB, C-term E.coli AGX-5-000-0117-0 GST 0.1 mg
    AGX-5-000-0117-1 GST 1.0 mg
Data sheet (87.3 KiB)
Safety data sheet (99.2 KiB)

Clostridium perfringens Heat-labile enterotoxin B chain (C-terminus)

  Expression system Article No. Fusion Quantity
CPE, C-term E.coli AGX-5-000-0882-0 6xHis 0.1 mg
    AGX-5-000-0882-1 6xHis 1.0 mg
Data sheet (87.5 KiB)
Safety data sheet (96.9 KiB)

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